Persistent sad, anxious or “empty” mood. Feelings of hopelessness, pessimism. Feelings of guilt, worthlessness, helplessness. Loss of interest or pleasure in hobbies and activities, including sex. Decreased energy, fatigue, feeling “slowed down”. Difficulty concentrating, remembering, making decisions. Insomnia, early-morning awakening, or oversleeping. Low appetite and weight loss or overeating and weight gain. Thoughts of death […]